SALIVARY GLAND TUMORS EBOOK DOWNLOAD
SALIVARY GLAND TUMORS EBOOK DOWNLOAD!
About 7 out of 10 salivary gland tumors start here. Most of these tumors are benign (not cancer), but the parotid glands still are where most malignant (cancerous) salivary gland tumors start. The submandibular glands are smaller and are below the jaw. They secrete saliva under the tongue. Most salivary gland tumors are benign and occur in the parotid glands. A painless salivary mass is the most common sign and is evaluated by fine-needle aspiration biopsy. Imaging with CT and MRI can be helpful. For malignant tumors, treatment is with excision and radiation. Head and Neck: Salivary gland tumors: an overview, Authors: Audrey Rousseau, Cécile Badoual. Published in: Atlas Genet Cytogenet Oncol Haematol.
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Salivary gland tumour - Wikipedia
The type of salivary gland the cancer is in. The type of cancer cells how they look under a microscope.
The patient's age and general health. Stages of Salivary Gland Salivary gland tumors Key Points After salivary gland cancer has been diagnosed, tests are done to find out if cancer cells have spread within the salivary gland or to other parts of the body.
There are three ways that cancer spreads in the body. Cancer may spread from where it began to other parts of the body.
The following stages are used for major salivary gland cancers: Stage I Stage III Stage IV After salivary gland cancer has been diagnosed, tests are done to find out if cancer cells have spread within the salivary salivary gland tumors or to other parts of the body.
Salivary Gland Cancer Treatment (PDQ®)—Patient Version - National Cancer Institute
The process used to find out if cancer has spread within the salivary glands or to other parts of the body is called staging. The information gathered from the staging process determines the stage of salivary gland tumors disease.
It is salivary gland tumors to know the stage in order to plan treatment. The following procedures may be used in the staging process: Computed tomography CT scan of the head and neck.
Upon neoplastic transformation, some of those cells may undergo divergent differentiation and acquire salivary gland tumors mesenchymal phenotype. Cytogenetics Pleomorphic adenoma presents with a highly specific and recurrent pattern of chromosome abnormalities.
Salivary Gland Tumors - Ear, Nose, and Throat Disorders - MSD Manual Professional Edition
Four major cytogenetic subgroups have been defined: Rearrangements of chromosome 8q12 in PA most often involve the 5' non-coding salivary gland tumors of PLAG1 pleomorphic adenoma gene The translocation partners most often involved are CTNNB1 encoding beta-1 catenin and LIFR leukemia inhibitory factor receptorresulting from translocations t 3;8 p21;q12 and t 5;8 p13;q12respectively.
PLAG1 is a developmentally regulated zinc finger gene that maps to 8q It is not expressed in normal salivary gland parenchyma. The gene product is a nuclear protein that functions as a DNA-binding transcription factor.
PLAG1 may play a role in PA pathogenesis by inducing growth factor production, hence cell proliferation. It was demonstrated by Western blot and immunohistochemical salivary gland tumors that PLAG1 expression was up-regulated in epithelial and myoepithelial cells, as well as in the mesenchymal component of PA.
Such r 8 p12q The breakpoints occur in the 5' non coding salivary gland tumors of both genes, leading to promoter substitution and activation of PLAG1 expression.
Cryptic, intrachromosomal 8q rearrangements have been reported in PAs with an apparently normal karyotype.